Drowsiness, dizziness, lightheadedness, blurred vision, constipation, or dry mouth may occur
To Prochlorperazine may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use
Feb 1, 2024 · For oral dosage forms (tablets): For severe nausea and vomiting: Adults and children 2 years of age and older and weighs more than 39 kilograms (kg) (85 pounds (lbs))—At first, 5 or 10 milligrams (mg) 3 or 4 times a day
Haloperidol prolongs the QT interval at cumulative intravenous doses as low as 2 mg, 57 but the usual antiemetic dose is 1 mg
Optimal accuracy is achieved in the 60 to 80 heart rate range
If higher-risk patients are to be discharged with a prescription for multiple doses of an antiemetic, it would be preferable to use agents such as promethazine or
Extrapyramidal effects, hypotension, QT prolongation, sedation: Prochlorperazine: 5 to 10 mg every 6 hours: $0
Ondansetron-Prochlorperazine: Known risk of TdP: Not included in lists: Major: Fair: 6 (2
Phaeochromocytoma
Prochlorperazine comes as a tablet to take by mouth and as a suppository to place in the rectum
Prochlorperazine may increase the risk of QT interval prolongation
This problem may lessen or go away after stopping this medicine (prochlorperazine tablets), but it may not go away
About prochlorperazine
It can also be given as an injection, but this is usually done in hospital Compazine; Descriptions
Prochlorperazine edisylate, 2-Chloro-10- [3- (4-methyl-1-piperazinyl)propyl]phenothiazine 1,2-ethanedisulfonate (1:1), has the following structural formula: Molecular
Boxed Warning
Prochlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation antipsychotic drug that is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia
Side Effects
Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or Prochlorperazine is a type of anti-emetic agent which blocks dopamine (a type of chemical messenger)
Biochemistry results (within last two weeks): sodium, potassium, urea, creatinine, eGFR [+ magnesium level if potassium (< 3
dryness of the mouth
1 Identification of patients with the highest risk of QT prolongation and associated adverse outcomes has been facilitated… Indications and Dosage
As prochlorperazine edisylate: Initially
There are things you can do to help cope with them: Feeling sleepy or drowsy
Speak to a doctor or pharmacist if the advice on how to cope does not help and a side effect is still bothering you or does not go away
A few people who took lithium along with a drug like this one had severe side effects and lasting brain damage
stomach pain
Children with short-term illnesses (such as a viral infection, dehydration) may be more sensitive to the side effects of this drug, especially nerve/muscle problems
It may also be used to treat dizziness associated with problems of the inner ear such as Meniere’s Syndrome
Prochlorperazine Promethazine Risperidone Sulpiride Trazodone Venlafaxine Amisulpride Chlorpromazine Citalopram Clomipramine Escitalopram Haloperidol reduce the risk of QT prolongation without compromising overall safety and efficacy
Child 1–11 years (body-weight 10 kg and above) 250 micrograms/kg 2–3 times a day
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